As a global pandemic disrupts people’s reality, some are turning to virtual reality to fight back. Nanome is helping scientists understand and design molecular structures related to SARS-CoV-2 — and you can too.
Using fragment-based lead discovery, scientists at Diamond Light Source have identified nearly 60 small organic compounds that bind with a weak affinity to an accessible active site in the SARS-CoV-2 main protease. Your charge is to grow or combine these fragments to produce a lead for a small molecule inhibitor that binds with a higher affinity. Upload your designs here by this weekend for synthesis and testing:
https://covid.postera.ai/covid
…Read more
Less…